|本期目录/Table of Contents|

 LI Wei,HAN Lei,QIAN Yongqiang,et al.Characteristics and Functions of NAC Transcription Factors in Plants[J].Chinese Journal of Applied & Environmental Biology,2011,17(04):596-606.[doi:10.3724/SP.J.1145.2011.00596]





Characteristics and Functions of NAC Transcription Factors in Plants
(中国林业科学研究院林业研究所,国家林业局林木培育重点实验室 北京 100091)
LI Wei HAN Lei QIAN Yongqiang SUN Zhenyuan
(Research Institute of Forestry, Chinese Academy of Forestry Sciences; Key Laboratory of Forest Cultivation, State Forestry Administration, Beijing 100091, China)
transcription factor NAC structure domain biotic function expression regulation
综述了NAC转录因子的发现及其家族成员、结构特点和生物学功能. NAC类蛋白是近年来发现的一类植物特有、数量众多的转录因子家族,其成员广泛分布于陆生植物中. NAC家族成员的N端具有一个保守的约150个氨基酸组成的NAC结构域,含有A、B、C、D、E 5个亚结构域,C端具有一个高度变异的转录激活区. 分析表明,NAC蛋白结构与其功能密切相关. NAC转录因子具有诸多方面的功能,如参与植物次生生长,在细胞分裂和植株衰老中发挥作用,参与激素调控和信号转导,参与矿质元素营养和农作物品质改良等. 同时,NACs还参与生物胁迫中植物的防御反应以及在非生物逆境中发挥作用. 目前对NAC基因的研究主要集中于模式植物拟南芥和水稻,对于NAC蛋白涉及的调控途径及其组成因子知之甚少,因此NAC基因的功能还有待深入研究;同时,利用基因工程手段导入或改良关键的NAC转录因子,使作物综合品质的提高已成为可能. 图2 表2 参87
The members, structure characteristics and biotic functions of NAC transcription factors were introduced and analyzed. NAC proteins, which distribute widely in many land plant species, constitute one of the largest families of plant-specific transcription factors. The NAC family members have a conservative NAC domain in N-terminal ends with about 150 amino acids including five subdomains of A, B, C, D and E and a highly various transcriptional activation domain in C-terminal ends. The structure of NAC proteins is related to specific biotic functions, and the NAC transcription factors are involved in various aspects, such as plant secondary growth, cell division and plant senesce, hormones regulation and signal transduction, mineral element nutrition and improvement of crop quality. Meanwhile, NACs participate in plant defense responses during biotic and abiotic stress process. The studies have been focused on the model plants Arabidopisis thaliana and Oryza sativa, and little is known about regulation route and composition of NACs factors. Therefore it is necessary to have an in-depth study to understand the gene functions of NACs. Nevertheless, they have been used in plant molecular breeding by genetic engineering for crop genetic improvement. Fig 2, Tab 2, Ref 87


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更新日期/Last Update: 2011-08-16