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Applications of conductive polymers in the biomedical field*(PDF)

Chinese Journal of Applied & Environmental Biology[ISSN:1006-687X/CN:51-1482/Q]

2019 06
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Applications of conductive polymers in the biomedical field*
SHU Haoran1 LIU Jianqiao1 WANG Xiaoling1 YONG Yuan2 HAN Lu1 LI Bangjing3 & GUO Kun1**
1 College of Pharmacy, Southwest Minzu University, Chengdu 610041, China
2 College of Chemistry and Environment Protection Engineering, Southwest Minzu University, Chengdu 610041, China
3 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
conducting polymers biosensors tissue engineering protein corona

Controlled release of drug is a novel important direction of the modern pharmacology, and carrier used in the drug delivery usually is polymeric functional material. The research and development of conducting polymers (CPs) have received considerable attention in the fields of biology, clinical medicine and biomedical engineering, due to the good conductivity, stable electrochemical properties and well biological compatibility. Therefore, it has been widely used in biomedical, such as biosensors, neural prosthesis, controlled release drug carriers and tissue scaffolds. In this paper, we review the research progress and trends of conductive polymers. We summarize the preparation and application of conductive polymers in the field of tissue engineering, regenerative medicine, and biological sensors and so on. Finally, we introduce their applications, such as protein corona. In the fields of tissue engineering and regenerative medicine, conductive polymers are mainly used for nerve regeneration, treatment of cardiovascular diseases and wound healing. In the field of biosensors, conductive polymers are mainly used to repair damaged nervous systems, promote DNA probe orientation binding, neuronal regeneration, and a series of stress metabolism markers for detecting lactic acid and glucose. As the electric functional materials, the research and development of conductive polymer are very rapid, and it is one of the future vital research directions to prepare conductive polymers with high value in application and excellent biocompatibility by simple method. We believe that the research on construction and application of conductive polymers will greatly promote the progress of functional materials, and can also expand the application prospect of conductive polymer materials in the biomedical field.




Last Update: 2019-04-30