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In Vitro Bioactivity of Different Extracts from Arenaria kansuensis Maxim(PDF)

Chinese Journal of Applied & Environmental Biology[ISSN:1006-687X/CN:51-1482/Q]

Issue:
2010 05
Page:
642-645
Research Field:
Articles
Publishing date:

Info

Title:
In Vitro Bioactivity of Different Extracts from Arenaria kansuensis Maxim
Author(s):
LIU XiaoxiaoWAN ZhenjiangDENG XiaoboSHI LinLU Xiaoxia
(1Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China)
(2Sichuan Boli Science & Technology Pharmaceutial Co. Ltd., Chengdu 610036, China)
Keywords:
Arenaria kansuensis Maxim aqueous extract alcohol extract biological activities
CLC:
R965.1
PACS:
DOI:
10.3724/SP.J.1145.2010.00642
DocumentCode:

Abstract:
Biological activities of aqueous extract and ethanol extract from Arenaria kansuensis Maxim, as well as the commercial available oral nutritional liquid, were screened by a variety of in vitro models including proliferative effects on protein tyrosine phosphatase, dipeptidyl peptidase IV, inhibition of α-glucosidase, enhancement of sensitivity of drug-resistant MCF-7/ADR tumor cells, anti-tumor cytotoxic activities on HepG2 liver carcinoma cells and marrow cells were evaluated. The results indicate that all the samples tested exhibit inhibition on protein tyrosine phosphatase, whereas no obvious effects were observed on the other models. In conclusion, the active components of A. kansuensis can be traced by the protein tyrosine phosphatase model. Tab 6, Ref 16

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Last Update: 2010-10-25