|Table of Contents|

EFFECTS OF VOLATILE OIL OF ORIGANUM VULGARE L.ON SPECIFIC IMMUNOLOGICAL FUNCTIONS IN MICE(PDF)

Chinese Journal of Applied & Environmental Biology[ISSN:1006-687X/CN:51-1482/Q]

Issue:
1997 04
Page:
389-391
Research Field:
Publishing date:

Info

Title:
EFFECTS OF VOLATILE OIL OF ORIGANUM VULGARE L.ON SPECIFIC IMMUNOLOGICAL FUNCTIONS IN MICE
Author(s):
Lin Qinghua Zhang Chufu Liu Yanwen
1. School of Life Science, Wuhan University, Wuhan 430072;
2. Hubei College of Traditional Chinese Medicine, Wuhan 430061
Keywords:
volatile oil of Origanum vulgare L.cell-mediated immunityhumoral immunityhemolysindelayed type hypersensitivity
CLC:
-
PACS:
DOI:
-
DocumentCode:

Abstract:
The experimental results showed that volatile oil of Origanum vulgare L.(VO) significantly inhibited skindelayed type hypersensitivity (DTH) of mice induced by Dinitrochlorobenzene (DNCB) and sheep red blood cell(SRBC), and also inhibited the production of hemolysin in serum and SRBC hemolysis mediated by spleen cells atthe same dose of 100 mg·kg-1×7 d ip.The results also indicated it could cause thymus and spleen atrophyin mice at the dose.When the dose of VO was reduced to 50 mg·kg-1·d-1×7 d ip, it significantly increasedthe level of hemolysin in the serum of the mice and SRBC hemolysis mediated by spleen cells.VO couldremarkably inhibited DTH in mice induced by DNCB and SRBC at the dose.It suggested that VO could inhibit specificCell-mediated immunity and had different effects on specific humoral immunity with different doses.

References

[1] 《全国中草药汇编》编写组.全国中草药汇编(上册).北京:人民卫生出版社,1976
[2] 林清华,刘波,徐有为等.牛至挥发油对肠炎常见菌的体外抗菌作用.应用与环境生物学报.19973(1):76~78
[3] 林清华,汤汉文,王礼德.牛至挥发油对小鼠腹腔巨噬细胞活性及免疫器官重量的影响.基础医学与临床.1990,10(1):49~51
[4] 林清华,付晓琴,冯敏燕等.羧甲基变性半纤维素对小鼠某些免疫功能的影响.生理科学.1987,7(5):291~293
[5] 邓文龙,刘家玉,聂仁吉.昆明山海棠的药理作用研究Ⅱ,对免疫功能的影响.中草药.1981,1200):26~30
[6] 李卓娅,冯新为.氰味咪胍对小鼠抗羊红细胞的细胞免疫与体液免疫的影响.上海免疫学杂志.1988.8(4):254~257
[7] 林飞卿,余传霖,何球藻主编.医学基础免疫学.上海:上海医科大学出版社.1992

Memo

Memo:
-
Last Update: 1900-01-01